What is DRPLA?
Dentatorubral-pallidoluysian atrophy, commonly known as DRPLA, is a progressive brain disorder that affects coordination, balance, speech, and causes involuntary movements, emotional problems, and a decline in thinking ability. The average age of onset of DRPLA is 30 years, but this condition can appear anytime from infancy to adulthood. The symptoms and progression vary depending on the age of onset.
What is CureDRPLA?
CureDRPLA is a US based non-profit founded by Paul and Andrea Compton. Paul and Andrea have a son that was diagnosed with DRPLA in August 2018. The mission of CureDRPLA is to connect families, physicians and scientific investigators to further DRPLA research and work towards a treatment for DRPLA. This webpage was created to find others that have this condition and are interested in finding a cure.
CureDRPLA
Global
Patient
Registry
The CureDRPLA Global Patient Registry is a worldwide registry of DRPLA patients.
This registry gathers the demographic and clinical information on DRPLA patients from across the globe. By collecting information on all DRPLA patients, the CureDRPLA Global Patient Registry will be a powerful resource for research and will enhance opportunities for treatment development.
Patient & Caregiver
Click below to find out what CureDRPLA has done and what we are currently doing to find to a treatment for DRPLA. You will also find online resources and support organizations for DRPLA as well as YouTube channels specifically focused on DRPLA.
Click below to find out what CureDRPLA has done and what we are currently doing to find a treatment for DRPLA. You will also find online resources and support organizations for DRPLA as well as YouTube channels specifically focused on DRPLA.
Patient &
Caregiver
Researcher
& Industry
CureDRPLA is investing in a number of projects in hopes of rapidly developing novel therapeutics for DRPLA. Information on funding opportunities, a list of our preclinical projects as well as other efforts can be found here.
Latest
News
American Epilepsy Society funds research project on DRPLA
CureDRPLA is honored to announce that the American Epilepsy Society, another non-profit organization, has awarded funding to a research project to better understand epilepsy in DRPLA cell lines and mouse models. Epilepsy is very common in people with juvenile-onset...
Watch the recording of the 2024 DRPLA Research Update Talk
Did you miss our meeting on December 4? Do not worry—we have got you covered! Dr Silvia Prades recorded her presentation to allow more people to learn about our work and updates. This talk included updates on our organization, the DRPLA Natural History and Biomarkers...
Showcased DRPLA research to 600 people at ataxia conference
The International Congress for Ataxia Research (ICAR) was held in London on November 12-15. This was the biggest gathering of people interested in ataxia, with 600 attendees from 32 countries. The audience included scientists, clinicians and representatives from...
Social
About DRPLA Centers of Excellence - CureDRPLA
curedrpla.org
DRPLA is a complex and heterogeneous condition that can impact many aspects of everyday life, thus individuals affected and their families require access to specialized care to better understand this ...
youtu.be
Our mission is to connect families, physicians and scientific investigators to further DRPLA research and work towards a treatment. In this video we provide ...
youtu.be
Our mission is to connect families, physicians and scientific investigators to further DRPLA research and work towards a treatment. In this video we provide ...
Join Our DRPLA Community Today
At CureDRPLA, we connect patients, families, clinicians and researchers to further DRPLA research and work towards a treatment for DRPLA. You can join our community by going to Rare Connect. For more information about our community, get in touch with us.