What is DRPLA?
Dentatorubral-pallidoluysian atrophy, commonly known as DRPLA, is a progressive brain disorder that affects coordination, balance, speech, and causes involuntary movements, emotional problems, and a decline in thinking ability. The average age of onset of DRPLA is 30 years, but this condition can appear anytime from infancy to adulthood. The symptoms and progression vary depending on the age of onset.
What is CureDRPLA?
CureDRPLA is a US based non-profit founded by Paul and Andrea Compton. Paul and Andrea have a son that was diagnosed with DRPLA in August 2018. The mission of CureDRPLA is to connect families, physicians and scientific investigators to further DRPLA research and work towards a treatment for DRPLA. This webpage was created to find others that have this condition and are interested in finding a cure.
CureDRPLA
Global
Patient
Registry
The CureDRPLA Global Patient Registry is a worldwide registry of DRPLA patients.
This registry gathers the demographic and clinical information on DRPLA patients from across the globe. By collecting information on all DRPLA patients, the CureDRPLA Global Patient Registry will be a powerful resource for research and will enhance opportunities for treatment development.
Patient & Caregiver
Click below to find out what CureDRPLA has done and what we are currently doing to find to a treatment for DRPLA. You will also find online resources and support organizations for DRPLA as well as YouTube channels specifically focused on DRPLA.
Click below to find out what CureDRPLA has done and what we are currently doing to find a treatment for DRPLA. You will also find online resources and support organizations for DRPLA as well as YouTube channels specifically focused on DRPLA.
Patient &
Caregiver
Researcher
& Industry
CureDRPLA is investing in a number of projects in hopes of rapidly developing novel therapeutics for DRPLA. Information on funding opportunities, a list of our preclinical projects as well as other efforts can be found here.
Latest
News
CureDRPLA has published a scientific article highlighting advances in research
We have been working with Ataxia UK and the scientific community from around the world to advance research on DRPLA. Our recent article, published in a scientific journal, highlights the strides we and our scientific community have made in understanding DRPLA and our...
Similarities and differences between DRPLA and Huntington’s disease
Dentatorubral-pallidoluysian atrophy (DRPLA) and Huntington's disease (HD) are rare genetic disorders affecting the brain, caused by a specific type of genetic change, an elongation of a repetitive stretch of the letters “C-A-G”. In DRPLA that expansion is found in...
Insights from the International Drug Repurposing conference
On March 6-7, 2024, the International Drug Repurposing conference took place in Barcelona, bringing together nearly 200 attendees. Among them was Dr. Silvia Prades, our Research Manager, representing our commitment to advancing research. Drug repurposing consists of...
Social
www.ataxia.org.uk
All About Ataxia & All About Ataxia PLUS All About Ataxia is an information seminar that gives anyone affected by ataxia (patients, carers/family members) information about the clinical and practical ...
Virtual Activities - Ataxia UK
www.ataxia.org.uk
Virtual activity groups for the Ataxia Community Our Virtual Activity groups started in the first Covid-19 lockdown and have been so popular that we've continued with them ever since. At Ataxia UK, we...
About DRPLA Centers of Excellence - CureDRPLA
curedrpla.org
DRPLA is a complex and heterogeneous condition that can impact many aspects of everyday life, thus individuals affected and their families require access to specialized care to better understand this ...
Join Our DRPLA Community Today
At CureDRPLA, we connect patients, families, clinicians and researchers to further DRPLA research and work towards a treatment for DRPLA. You can join our community by going to Rare Connect. For more information about our community, get in touch with us.